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  2. Effects of nicotine on human brain development - Wikipedia

    en.wikipedia.org/wiki/Effects_of_nicotine_on...

    A 2015 review concluded that "Nicotine acts as a gateway drug on the brain, and this effect is likely to occur whether the exposure is from smoking tobacco, passive tobacco smoke or e-cigarettes." [25] Nicotine may have a profound impact on sleep. [26] The effects on sleep vary after being intoxicated, during withdrawal, and from long-term use ...

  3. Addiction-related structural neuroplasticity - Wikipedia

    en.wikipedia.org/wiki/Addiction-related...

    Addiction-related structural neuroplasticity. Addiction is a state characterized by compulsive engagement in rewarding stimuli, despite adverse consequences. The process of developing an addiction occurs through instrumental learning, which is otherwise known as operant conditioning . Neuroscientists believe that drug addicts’ behavior is a ...

  4. Substance dependence - Wikipedia

    en.wikipedia.org/wiki/Substance_dependence

    Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...

  5. Addiction - Wikipedia

    en.wikipedia.org/wiki/Addiction

    Drug addiction, which belongs to the class of substance-related disorders, is a chronic and relapsing brain disorder that features drug seeking and drug abuse, despite their harmful effects. [25] This form of addiction changes brain circuitry such that the brain's reward system is compromised, [ 26 ] causing functional consequences for stress ...

  6. Neuropharmacology - Wikipedia

    en.wikipedia.org/wiki/Neuropharmacology

    Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. [2] Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have ...

  7. Alcohol-related brain damage - Wikipedia

    en.wikipedia.org/wiki/Alcohol-related_brain_damage

    Alcohol-related brain damage[ 1][ 2] alters both the structure and function of the brain as a result of the direct neurotoxic effects of alcohol intoxication or acute alcohol withdrawal. Increased alcohol intake is associated with damage to brain regions including the frontal lobe, [ 3] limbic system, and cerebellum, [ 4] with widespread ...

  8. Addiction psychology - Wikipedia

    en.wikipedia.org/wiki/Addiction_psychology

    Addiction affects the brain circuits of reward and motivation, learning and memory, and the inhibitory control over behavior. [24] There are different schools of thought regarding the terms dependence and addiction when referring to drugs and behaviors. One adopted belief is that "drug dependence" equals "addiction."

  9. Nicotine dependence - Wikipedia

    en.wikipedia.org/wiki/Nicotine_dependence

    A National Institute on Drug Abuse video entitled Anyone Can Become Addicted to Drugs. [18]Nicotine dependence is defined as a neurobiological adaptation to repeated drug exposure that is manifested by highly controlled or compulsive use, the development of tolerance, experiencing withdrawal symptoms upon cessation including cravings, and an inability to quit despite harmful effects. [6]