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Medical genetics. Named after. Donovan James McCune. Fuller Albright. McCune–Albright syndrome is a complex genetic disorder affecting the bone, skin and endocrine systems. It is a mosaic disease arising from somatic activating mutations in GNAS, which encodes the alpha-subunit of the G s heterotrimeric G protein. [ 1]
Mongolian spot is a congenital developmental condition—that is, one existing from birth—exclusively involving the skin. The blue colour is caused by melanocytes, melanin -containing cells, that are usually located in the surface of the skin (the epidermis ), but are in the deeper region (the dermis) in the location of the spot. [ 6]
Café au lait spots, or café au lait macules, are flat, hyperpigmented birthmarks. [ 1] The name café au lait is French for "coffee with milk" and refers to their light-brown color. They are caused by a collection of pigment-producing melanocytes in the epidermis of the skin. [ 2] These spots are typically permanent and may grow or increase ...
Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis. Melanin is a class of pigment responsible for producing color in the body in places such as the eyes, skin, and hair. The process of melanin synthesis (melanogenesis ...
A birthmark is a congenital, benign irregularity on the skin which is present at birth or appears shortly after birth—usually in the first month. Birthmarks can occur anywhere on the skin. [ 1] They are caused by overgrowth of blood vessels, melanocytes, smooth muscle, fat, fibroblasts, or keratinocytes . Dermatologists divide birthmarks into ...
Fade dark spots with proven solutions from top experts including dermatologists and aestheticians. Skip to main content. Sign in. Mail. 24/7 Help. For premium support please call: 800-290 ...
The area of skin affected grows in proportion to general growth. Port-wine stains occur most often on the face but can appear anywhere on the body, particularly on the neck, upper trunk, arms and legs. [2] [4] Early stains are usually flat and pink in appearance. As the child matures, the color may deepen to a dark red or purplish color. [2]
The above ingredients can be incorporated into a daily skin care routine to help reduce the look of sun spots on your face over time, Hu says. But a dermatologist can offer other treatments to ...