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Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis. Melanin is a class of pigment responsible for producing color in the body in places such as the eyes, skin, and hair. The process of melanin synthesis (melanogenesis ...
Specialty. Dermatology. Dermatosis papulosa nigra (DPN) is a condition of many small, benign skin lesions on the face, a condition generally presenting on dark-skinned individuals. [ 1]: 638–9 DPN is extremely common, affecting up to 30% of Black people in the US. [ 2] From a histological perspective, DPN resembles seborrheic keratoses. [ 3]
Freckle. Freckles are clusters of concentrated melaninized cells which are most easily visible on people with a fair complexion. Freckles do not have an increased number of the melanin-producing cells, or melanocytes, but instead have melanocytes that overproduce melanin granules ( melanosomes) changing the coloration of the outer skin cells ...
Schamberg's disease, or progressive pigmented purpuric dermatosis, is a chronic discoloration of the skin which usually affects the legs and often spreads slowly. This disease is more common in males and may occur at any age from childhood onward. This condition is observed worldwide and has nothing to do with race or ethnic background.
Fade dark spots with proven solutions from top experts including dermatologists and aestheticians. Skip to main content. Sign in. Mail. 24/7 Help. For premium support please call: 800-290 ...
Noonan syndrome with multiple lentigines ( NSML) which is part of a group called Ras / MAPK pathway syndromes, [2] is a rare autosomal dominant, [3] multisystem disease caused by a mutation in the protein tyrosine phosphatase, non-receptor type 11 gene ( PTPN11 ). The disease is a complex of features, mostly involving the skin, skeletal and ...
Mandelic acid works as a sensitive-skin-friendly exfoliant to brighten dark spots and sun damage. When using products with these ingredients consistently, you should start to see some improvement ...
Urticaria pigmentosa. Urticaria pigmentosa (also known as generalized eruption of cutaneous mastocytosis (childhood type)[ 1]: 616 ) is the most common form of cutaneous mastocytosis. It is a rare disease caused by excessive numbers of mast cells in the skin that produce hives or lesions on the skin when irritated.