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5-HT receptors, 5-hydroxytryptamine receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems. [ 1 ] [ 2 ] [ 3 ] They mediate both excitatory and inhibitory neurotransmission .
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Some channels conduct multiple ion currents and some are gated by multiple mechanisms. Examples of targets for modulators include: Voltage-gated ion channels. Calcium channel: see also Calcium channel blocker, Calcium channel opener; Potassium channel: see also Potassium channel blocker, Potassium channel opener; Sodium channel: see also Sodium ...
The two-pore-domain or tandem pore domain potassium channels are a family of 15 members that form what is known as leak channels which possess Goldman-Hodgkin-Katz (open) rectification. [1] These channels are regulated by several mechanisms including signaling lipids , oxygen tension , pH , mechanical stretch , and G-proteins . [ 2 ]
Ion Jalea (Romanian pronunciation: [iˈon ˈʒale̯a]; 19 May 1887 – 7 November 1983) was a Romanian sculptor, monumentalist, teacher, and member of the Romanian Academy. He fought in the First World War and lost his left hand in battle. Despite this challenge, he continued to sculpt with his right hand for the rest of his life.
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Ion Druță (3 September 1928 – 28 September 2023), also known as Ion Drutse, was a Moldovan writer, poet, playwright and literary historian. He was an honorary member of the Romanian Academy . Biography
Title Year A Golden Christmas: 2009 Christmas Mail: 2010 12 Wishes of Christmas: 2011 Mandie and the Forgotten Christmas: 2011 Holiday Heist: 2011 A Golden Christmas 2