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Alcohol intoxication, also known in overdose as alcohol poisoning, [ 1] commonly described as drunkenness or inebriation, [ 9] is the behavior and physical effects caused by a recent consumption of alcohol. [ 6][ 10] In addition to the toxicity of ethanol, the main psychoactive component of alcoholic beverages, other physiological symptoms may ...
The Alcohol Use Disorders Identification Test (AUDIT) is a ten-item questionnaire approved by the World Health Organization to screen patients for hazardous (risky) and harmful alcohol consumption. It was developed from a WHO multi-country collaborative study, [ 1 ] [ 2 ] [ 3 ] the items being selected for the AUDIT being the best performing of ...
Idiosyncratic drug reactions, also known as type B reactions, are drug reactions that occur rarely and unpredictably amongst the population. This is not to be mistaken with idiopathic, which implies that the cause is not known. They frequently occur with exposure to new drugs, as they have not been fully tested and the full range of possible ...
Alcohol-related brain damage[ 1][ 2] alters both the structure and function of the brain as a result of the direct neurotoxic effects of alcohol intoxication or acute alcohol withdrawal. Increased alcohol intake is associated with damage to brain regions including the frontal lobe, [ 3] limbic system, and cerebellum, [ 4] with widespread ...
Avoiding or restricting alcohol is the most straightforward way to prevent the symptoms of alcohol intolerance. [5] [6] [13] Tobacco use or exposure to secondhand smoke should be avoided, as smoking may increase levels of acetaldehyde. Certain medications may interact with alcohol and worsen symptoms.
Hepatogenous poisoning. Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval.
Acute liver failure is the appearance of severe complications rapidly after the first signs (such as jaundice) of liver disease, and indicates that the liver has sustained severe damage (loss of function of 80–90% of liver cells). The complications are hepatic encephalopathy and impaired protein synthesis (as measured by the levels of serum ...
Alcoholic ketoacidosis. Alcoholic ketoacidosis ( AKA) is a specific group of symptoms and metabolic state related to alcohol use. [ 3] Symptoms often include abdominal pain, vomiting, agitation, a fast respiratory rate, and a specific "fruity" smell. [ 2] Consciousness is generally normal. [ 1]