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Watson and Clark (1991) proposed the Tripartite Model of Anxiety and Depression to help explain the comorbidity between anxious and depressive symptoms and disorders. [1] This model divides the symptoms of anxiety and depression into three groups: negative affect, positive affect and physiological hyperarousal. [1][2][3] These three sets of ...
Serotonin transporter. The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that in humans is encoded by the SLC6A4 gene. [5] SERT is a type of monoamine transporter protein that transports the neurotransmitter serotonin from the synaptic cleft back ...
Biology of depression. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD), [ 1 ] and this has encouraged advocates of various theories that seek to identify a biochemical origin of the disease, as opposed to theories that emphasize psychological or situational causes.
Long-term depression. In neurophysiology, long-term depression (LTD) is an activity-dependent reduction in the efficacy of neuronal synapses lasting hours or longer following a long patterned stimulus. LTD occurs in many areas of the CNS with varying mechanisms depending upon brain region and developmental progress. [1]
We’ve all felt the discomfort of anxiety. Neuroscientist Dr. Wendy Suzuki has five tips to harness the positive side of what she calls the most misunderstood emotion. Transform your anxiety into ...
Many professionals believe that the cause of mental disorders is the biology of the brain and the nervous system. Mind mentions genetic factors, long-term physical health conditions, and head injuries or epilepsy (affecting behavior and mood) as factors that may trigger an episode of mental illness.
Depressive anxiety is a term developed in relation to the depressive position by Melanie Klein, building on Freud's seminal article on object relations of 1917, 'Mourning and Melancholia'. [1] Depressive anxiety revolved around a felt state of inner danger produced by the fear of having harmed good internal objects [ 2 ] - as opposed to the ...
Evolutionary approaches to depression. Evolutionary approaches to depression are attempts by evolutionary psychologists to use the theory of evolution to shed light on the problem of mood disorders within the perspective of evolutionary psychiatry. Depression is generally thought of as dysfunction or a mental disorder, but its prevalence does ...