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Basophilic stippling, also known as punctate basophilia, is the presence of numerous basophilic granules that are dispersed through the cytoplasm of erythrocytes in a peripheral blood smear. They can be demonstrated to be RNA .
Features of poisoning differ depending on whether the agent is an organic compound (one that contains carbon), or an inorganic one. [29] Organic lead poisoning is now very rare, because countries across the world have phased out the use of organic lead compounds as gasoline additives, but such compounds are still used in industrial settings. [29]
A cell containing Pappenheimer bodies is a siderocyte. Reticulocytes often contain Pappenheimer bodies. They are mostly observed in diseases such as myelodysplastic syndrome (MDS), sideroblastic anemia, hemolytic anemia, lead poisoning and sickle cell disease. They can interfere with platelet counts when the analysis is performed by electro ...
Basophilic stippling is marked and target cells are common. The mean cell volume is commonly decreased (i.e., a microcytic anemia), but it may also be normal or even high. The RDW is increased with the red blood cell histogram shifted to the left. Leukocytes and platelets are normal. Bone marrow shows erythroid hyperplasia with a maturation ...
Lead poisoning is most commonly caused by breathing in lead dust or particles, but it can also occur by touching a surface where lead is present, then touching one’s nose or mouth, ...
Metal toxicity or metal poisoning is the toxic effect of certain metals in certain forms and doses on life.Some metals are toxic when they form poisonous soluble compounds. . Certain metals have no biological role, i.e. are not essential minerals, or are toxic when in a certain for
Rare acquired causes of microcytic anemia include lead poisoning, zinc deficiency, copper deficiency, alcohol, and certain medications. [3] Other causes that are typically thought of as causing normocytic anemia or macrocytic anemia must also be considered, as the presence of two or more causes of anemia can distort the typical picture.
Lead poisoning epidemics refer to specific instances of mass lead poisoning. These events often occur without the knowledge of the communities they affect. Common causes of lead poisoning epidemics include mining, lead recycling, and food/water contamination. [1] These events also cause disproportionate childhood fatalities as children are more ...