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  2. Tafamidis - Wikipedia

    en.wikipedia.org/wiki/Tafamidis

    Tafamidis, sold under the brand names Vyndaqel and Vyndamax, [5] is a medication used to delay disease progression in adults with certain forms of transthyretin amyloidosis. It can be used to treat both hereditary forms, familial amyloid cardiomyopathy and familial amyloid polyneuropathy , as well as wild-type transthyretin amyloidosis , which ...

  3. Familial amyloid polyneuropathy - Wikipedia

    en.wikipedia.org/wiki/Familial_amyloid_poly...

    The committee stated that there was not enough evidence supporting efficacy of the drug, and requested additional clinical trials. [14] In May 2019, the FDA approved two tafamidis preparations for the treatment of transthyretin-mediated cardiomyopathy, but has not approved it for the treatment of transthyretin familial amyloid polyneuropathy.

  4. Clark's rule - Wikipedia

    en.wikipedia.org/wiki/Clark's_rule

    Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK, the West Indies ...

  5. Alnylam's Biggest Opportunities - AOL

    www.aol.com/news/2013-10-01-alnylams-biggest...

    On the other hand, Pfizer's Vyndaqel is the first drug used for treatment of FAP, one of two forms of ATTR. The product is approved only in Europe. Prior to Vyndaqel, liver transplantation was the ...

  6. 3 Dirt Cheap Stocks to Buy Right Now - AOL

    www.aol.com/3-dirt-cheap-stocks-buy-113600246.html

    It dramatically reduced infections by 96% in a phase 3 trial. Analysts estimate that the drug, which is already approved to treat people who have multidrug-resistant HIV, could generate $4 billion ...

  7. Boy, 8, dies after pharmacy allegedly gave medication dosage ...

    www.aol.com/article/2016/06/20/boy-8-dies-after...

    8-Year-Old Dies After Pharmacy Allegedly Gave Dosage 1,000 More Than Prescribed An 8-year-old boy died after a Colorado pharmacy gave him a dosage of medication 1,000 times higher than what he was ...

  8. Dosage (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Dosage_(pharmacology)

    In pharmacology and medicine, dosage refers to the prescribed regimen for administering a medication or substance, encompassing the amount, frequency, and duration of use. [1] It is distinct from dose , which denotes a single, specific quantity of a drug or substance given at one time. [ 2 ]

  9. Dose (biochemistry) - Wikipedia

    en.wikipedia.org/wiki/Dose_(biochemistry)

    This cuts the dose in half. Prescription drug doses are often based on body weight. [3] Drugs come with a recommended dose in milligrams or micrograms per kilogram of body weight, and that is used in conjunction with the patient's age and body weight to determine a safe dose.