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Intravaginal administration is a route of administration where the substance is applied inside the vagina. Pharmacologically , it has the potential advantage to result in effects primarily in the vagina or nearby structures (such as the vaginal portion of cervix ) with limited systemic adverse effects compared to other routes of administration.
In addition, bacterial vaginosis as either pre-existing, or acquired, may increase the risk of pregnancy complications, most notably premature birth or miscarriage. [25] [26] Pregnant women with BV have a higher risk of chorioamnionitis, miscarriage, preterm birth, premature rupture of membranes, and postpartum endometritis. [27]
Metronidazole, sold under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. [10] It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. [10]
Bacterial vaginosis in pregnancy is an alteration of the normal vaginal microbiota of pregnancy. Intrauterine infections in pregnancy are caused by bacteria that cause inflammation. The women may experience few or no symptoms. This sometimes leads to chorioamnionitis and other negative pregnancy outcomes.
A sensitive serum pregnancy test is typically obtained to rule out ectopic pregnancy. Culdocentesis will differentiate hemoperitoneum (ruptured ectopic pregnancy or hemorrhagic cyst) from pelvic sepsis (salpingitis, ruptured pelvic abscess, or ruptured appendix). [28] Pelvic and vaginal ultrasounds are helpful in the diagnosis of PID.
A miscarriage, which is also known as an early pregnancy loss, is the unexpected loss of a pregnancy before the 20-week mark, according to the Cleveland Clinic.
APIA, Samoa (Reuters) -Commonwealth leaders, ending a week-long summit in Samoa, said on Saturday the time had come for a discussion on whether Britain should commit to reparations for its role in ...
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