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“Before menopause, the main hormone is estrogen, and after menopause, androgens like testosterone become more prevalent,” Stanhiser says. In that case, can testosterone treat menopause symptoms?
Fat cells have a high amount of aromatase, an enzyme that converts testosterone into estrogen (while estrogen is the primary female sex hormone, men need it too, in small amounts).
Aromatase is localized in the endoplasmic reticulum where it is regulated by tissue-specific promoters that are in turn controlled by hormones, cytokines, and other factors. It catalyzes the last steps of estrogen biosynthesis from androgens (specifically, it transforms androstenedione to estrone and testosterone to estradiol).
Testosterone, which is produced in the testicles, naturally declines as you age, Dr. El-Zawahry says. After your 30s or 40s, you can expect it to drop about 1 percent to 3 percent a year. Aging is ...
Testosterone is the primary male sex hormone and androgen in males. [3] In humans, testosterone plays a key role in the development of male reproductive tissues such as testicles and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair.
Phthalates inhibit testosterone synthesis and decrease the production of natural androgens in the body. [2] Dioxins and some organochlorine pesticides (OCPs) can cause increased metabolism of estrogen, decreasing the amount of estrogen in the body. [2] Xenohormones can also alter the expression of hormone receptors to either increase or ...
A drastic drop in testosterone can quickly turn your sex drive into a sex putter. ... testosterone and estrogen levels can increase body fat. High aromatase and estrogen activity reduces the ...
In premenopausal women the majority of estrogen produced by the body is estradiol (produced primarily in the ovaries), while in postmenopausal women estrone (produced in fat cells) is the type of primary estrogen present; however, the body is able to convert one type of estrogen into another to a certain extent.
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