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The concerns began with the hypothesis that BPA is an endocrine disruptor, i.e. it mimics endocrine hormones and thus has the unintended and possibly far-reaching effects on people in physical contact with the chemical. Since 2008, several governments have investigated its safety, which prompted some retailers to withdraw polycarbonate products.
The chemicals are called EDCs, and they are likely already in your home. Here’s what researchers know about their potential health impacts and what to do about them.
Endocrine disruptors are chemicals that interfere with our endocrine systems, which control the body’s hormones—such as insulin, testosterone, and estrogen—and numerous bodily functions ...
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In this way, xenohormones act as endocrine disruptors by increasing or decreasing the activation of hormone receptors in the body. Xenohormones can often act on multiple hormone receptor types and enact multiple different effects. For example, BPA acts as an agonist of estrogen receptors and as an antagonist of androgen receptors. [15]
Bisphenol A (BPA) is a chemical compound primarily used in the manufacturing of various plastics. It is a colourless solid which is soluble in most common organic solvents, but has very poor solubility in water. [2] [7] BPA is produced on an industrial scale by the condensation reaction of phenol and acetone. Global production in 2022 was ...
A comparison of the structures of the natural estrogen hormone estradiol (left) and one of the nonyl-phenols (right), a xenoestrogen endocrine disruptor. Endocrine disruptors, sometimes also referred to as hormonally active agents, [1] endocrine disrupting chemicals, [2] or endocrine disrupting compounds [3] are chemicals that can interfere with endocrine (or hormonal) systems. [4]
Endocrine-disrupting chemicals like BPA, phthalates, and PFAS are widespread in consumer products ... Since endocrine disruptors interfere with sex steroid hormones, sex differences can be ...