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Inflammation is a general marker of tissue damage in any disease, and may be either secondary to tissue damage in Alzheimer's disease or a marker of an immunological response. [146] There is increasing evidence of a strong interaction between the neurons and the immunological mechanisms in the brain.
Alzheimer's disease (AD) is a progressive, degenerative and fatal brain disease, in which cell to cell connections in the brain are lost. Alzheimer's disease is the most common form of dementia. [2] Globally approximately 1–5% of the population is affected by Alzheimer's disease. [3] Women are disproportionately affected by Alzheimer's disease.
Brain damage, dementia, [2] aggression, depression, suicide [3] Usual onset: Years after initial injuries [2] Causes: Repeated head injuries [1] Risk factors: Contact sports, military service, repeated banging of the head [1] Diagnostic method: Autopsy [1] Differential diagnosis: Alzheimer's disease, Parkinson's disease [3] Treatment ...
There is a potential link between Alzheimer's disease and the herpes simplex virus-1 ... In his view: “Viral encephalitis causes confusion due to brain damage, not dementia. There is no clinical ...
[70] [68] Increased oxidative DNA damage in the brain is associated with Alzheimer's disease and Parkinson's disease. [70] Defective DNA repair has been linked to neurodegenerative disorders such as Alzheimer's disease, amyotrophic lateral sclerosis, ataxia telangiectasia, Cockayne syndrome, Parkinson's disease and xeroderma pigmentosum. [70] [69]
Anterograde amnesia can be the first clinical sign that Alzheimer's disease is developing within the brain. Although later the complications can be much more widespread and strongly impair cognitive processes, at the initial stage of Alzheimer's the changes observed can be restricted to anterograde amnesia and a mild deficit in retaining newly ...
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