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Monoamine reuptake inhibitors, including DRIs, have proven quite effective in managing excessive food consumption and regulating appetite in obese patients. Though such pharmacotherapy is still available, the majority of stimulant anorectics marketed for this purpose have been withdrawn or discontinued due to adverse side effects such as ...
One theory to explain antidepressant-related weight gain is that psychotropic medications such as antidepressants can affect neurotransmitters involved in eating behavior, causing an increase in ...
Also, currently available antidepressants all elicit undesirable side-effects, and new agents should be divested of the distressing side-effects of both first and second-generation antidepressants. [6] Another serious drawback of all antidepressants is the requirement for long-term administration prior to maximal therapeutic efficacy.
Why do antidepressants contribute to weight gain? Science doesn’t yet know, Perlis said. “Remarkably, we don’t know the precise mechanism by which antidepressants contribute to weight changes.
Elevation of norepinephrine levels can sometimes cause anxiety, mildly elevated pulse, and elevated blood pressure. However, norepinephrine-selective antidepressants, such as reboxetine and desipramine, have successfully treated anxiety disorders. [70] People at risk for hypertension and heart disease should monitor their blood pressure.
Regardless of what it’s treating, there are several reasons why you may want to switch antidepressants, from side effects to a lack of effectiveness. Some of the most common reasons to change ...
Fluoxetine, sold under the brand name Prozac, among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [2] It is used for the treatment of major depressive disorder, obsessive–compulsive disorder (OCD), anxiety, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. [2]
We also know that combining St. John’s wort with certain antidepressants may lead to a potentially life-threatening increase in serotonin, causing side effects like agitation, diarrhea, fast ...