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Poliomyelitis (/ ˌ p oʊ l i oʊ ˌ m aɪ ə ˈ l aɪ t ɪ s / POH-lee-oh-MY-ə-LY-tiss), commonly shortened to polio, is an infectious disease caused by the poliovirus. [1] Approximately 75% of cases are asymptomatic; [5] mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe symptoms develop such as headache, neck stiffness, and paresthesia.
The protein has several domains of which domain D1 contains the polio virus binding site. Within this domain, 37 amino acids are responsible for binding the virus. Poliovirus is an enterovirus. Infection occurs via the fecal–oral route, meaning that one ingests the virus and viral replication occurs in the gastrointestinal tract. [42]
Polio is an infection caused by a virus that mostly affects children under 5. Most people infected with polio don’t have any symptoms, but it can cause fever, headaches, vomiting and stiffness ...
Historically, poliomyelitis was the most significant disease caused by an enterovirus, namely poliovirus. There are 81 non-polio and 3 polio enteroviruses that can cause disease in humans. Of the 81 non-polio types, there are 22 Coxsackie A viruses, 6 Coxsackie B viruses, 28 echoviruses, and 25 other enteroviruses. [3]
An unvaccinated NY man has polio, the first documented case in the U.S. since 2013. Here, doctors explain what polio is, its causes, symptoms, and vaccines.
An emergency polio ward in Boston in 1955 equipped with iron lungs. These pressurized respirators acted as breathing muscles for polio victims, often children, who were paralyzed. www.apimages ...
The virus is most often spread by person to person contact with the stool or saliva of the infected person. Two types of vaccines have been developed to prevent the occurrence and spread of the poliomyelitis virus. The first is an inactivated, or killed, form of the virus and the second is an attenuated, or weakened, form of the virus.
In comparison, polio viruses linked to the vaccine caused more than 500 cases in nearly two dozen countries globally, mostly in Africa. Zimbabwe last reported a wild polio virus case in 1986 ...