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Lung cancer most commonly metastasizes to the brain, bones, liver, and adrenal glands. [14] Lung cancer can often appear as a solitary pulmonary nodule on a chest radiograph or CT scan. In lung cancer screening studies as many as 30% of those screened have a lung nodule, the majority of which turn out to be benign. [15]
For example, this can reveal if lung cancer was caused by tobacco smoke, if skin cancer was caused by UV radiation, or if secondary cancers were caused by previous chemotherapy treatment. [46] Cancer is generally not a transmissible disease. [47] Exceptions include rare transmissions that occur with pregnancies and occasional organ donors.
Squamous-cell carcinoma of the lung is closely correlated with a history of tobacco smoking, more so than most other types of lung cancer.According to the Nurses' Health Study, the relative risk of SCC is approximately 5.5, both among those with a previous duration of smoking of 1 to 20 years, and those with 20 to 30 years, compared to never-smokers. [2]
The signs and symptoms of this specific type of lung cancer are similar to other forms of lung cancer, and patients most commonly complain of persistent cough and shortness of breath. Adenocarcinoma is more common in patients with a history of cigarette smoking, and is the most common form of lung cancer in younger women and Asian populations.
Men who currently smoke tobacco develop lung cancer at a rate 14 times that of men who have never smoked tobacco: the chance of lung cancer in a current smoker being caused by smoking is about 93%; there is a 7% chance that the smoker's lung cancer was caused by radon gas or some other, non-tobacco cause. [34]
The Wynder and Graham 1950 study was able to conclude that "smoking was an important factor in the production of bronchogenic carcinoma," but smoking wasn't established as a causal factor until four years later, when Wynder published another paper entitled, "Tobacco as a Cause of Lung Cancer" [8] The same year Wynder and Graham published their ...
We've made massive strides against the deadly disease, but rates haven't fallen for people diagnosed with the disease who've never smoked.
The incidence of lung cancer is highly correlated with smoking. Tobacco smoking is associated with many forms of cancer, [20] and causes 80% of lung cancer. [21] Decades of research has demonstrated the link between tobacco use and cancer in the lung, larynx, head, neck, stomach, bladder, kidney, esophagus and pancreas. [22]
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