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Neuropixels probes (or "Neuropixels") are electrodes developed in 2017 to record the activity of hundreds of neurons in the brain. The probes are based on CMOS technology and have 1,000 recording sites arranged in two rows on a thin, 1-cm long shank.
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Chang has made fundamental contributions to understanding the neural code of speech and neuropsychiatric conditions in the human brain. [5]Chang pioneered the use of high-density direct electrophysiological recordings from cortex, which enabled him and colleagues to determine the selective tuning of cortical neurons to specific acoustic and phonetic features in consonants and vowels. [6]
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The researchers used RNA sequencing and brain-mapping tools to analyze more than 1.2 million brain cells from young mice (2 months old) and older mice (18 months old).