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The results of a key Alzheimer's drug trial on Wednesday have reignited decades-old hopes that targeting a particular protein helps arrest the progression of the fatal brain disease, giving a big ...
In 1976, neurologist Robert Katzmann suggested a link between senile dementia and Alzheimer's disease. [287] Katzmann suggested that much of the senile dementia occurring (by definition) after the age of 65, was pathologically identical with Alzheimer's disease occurring in people under age 65 and therefore should not be treated differently. [288]
Experts have hailed the “beginning of the end” in the search for effective Alzheimer’s treatments after a new drug reduced memory decline among patients with early stages of the disease ...
The term senile dementia of the Alzheimer type (SDAT) was used for a time to describe the condition in those over 65, with classical Alzheimer's disease being used to describe those who were younger. Eventually, the term Alzheimer's disease was formally adopted in medical nomenclature to describe individuals of all ages with a characteristic ...
Fischer supposedly (like Alois Alzheimer) employed new staining and autopsy results, and described "senile plaques" that are still accepted as the characteristic of the disease in addition to "neurofibrillary tangles" discovered by Alzheimer. [5] Both Fischer and Alzheimer argued that senile plaques may be formed by microorganisms. [10]
Compared to late onset dementia, patients with early onset dementia are more likely to have dementias other than Alzheimer's disease, although Alzheimer's is the most common etiology in either case. [13] In general, early onset dementia has a faster progression and features more extensive neurological damage when compared to late onset dementia.
From the age of 60 years (10%) to the age of 80 years (60%), the proportion of people with senile plaques increases linearly. Women are slightly more likely to have plaques than are men. [45] [44] Both plaques and Alzheimer's disease also are more common in aging persons with trisomy-21 (Down syndrome).
Stanley White was on a morning jog near his home when the first symptoms hit. White was only in his mid-50s at the time and knew of no health problems that could explain his falls. White’s ...