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7274 50500 Ensembl ENSG00000137561 ENSMUSG00000073988 UniProt P49638 Q8BWP5 RefSeq (mRNA) NM_000370 NM_015767 NM_001317723 RefSeq (protein) NP_000361 NP_001304652 NP_056582 Location (UCSC) Chr 8: 63.05 – 63.09 Mb Chr 4: 20.01 – 20.03 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Alpha- tocopherol transfer protein (α-TTP) is a protein that in humans is encoded by the TTPA gene ...
The three unnatural "2R" stereoisomers with natural R configuration at this 2' stereocenter, but S at one of the other centers in the tail (i.e., RSR, RRS, RSS), appear to retain substantial RRR vitamin activity, because they are recognized by the alpha-tocopherol transfer protein, and thus maintained in the plasma, where the other four ...
α-Tocopherol (alpha-tocopherol) is a type of vitamin E.Its E number is "E307". Vitamin E exists in eight different forms, four tocopherols and four tocotrienols.All feature a chromane ring, with a hydroxyl group that can donate a hydrogen atom to reduce free radicals and a hydrophobic side chain, along with an aromatic ring is situated near the carbonyls in the fatty acyl chains of the ...
Azzi's work focuses on the biochemistry of enzymes, gene regulation, and metabolism, with an emphasis on vitamin E (alpha-tocopherol), antioxidants, and signaling pathways involving protein kinase C and diacylglycerol kinase. [3]
Alpha-tocopherol transfer protein is coded by the TTPA gene on chromosome 8. The binding site for RRR-α-tocopherol is a hydrophobic pocket with a lower affinity for beta-, gamma-, or delta-tocopherols, or for the stereoisomers with an S configuration at the chiral 2 site.
Tocopherol (alpha) transfer protein-like is a protein that in humans is encoded by the TTPAL gene. [1] TTPAL; Identifiers, C20orf121, tocopherol (alpha ...
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