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For example, exposure to byproducts of water chlorination can obviously occur by drinking, but also through the skin, while swimming or washing, and even through inhalation from droplets aerosolized during a shower. The relative proportion of exposure from these different routes cannot be determined a priori. Therefore, the equation in the ...
The most common exposure route to chemicals in the work environment is through inhalation. [4] Gas, vapour, mist, dust, fumes, and smoke can all be inhaled. Those with occupations involving physical work may inhale higher levels of chemicals if working in an area with contaminated air.
Inhalation is a major route of exposure that occurs when an individual breathes in polluted air which enters the respiratory tract. Identification of the pollutant uptake by the respiratory system can determine how the resulting exposure contributes to the dose. In this way, the mechanism of pollutant uptake by the respiratory system can be ...
In pharmacology and toxicology, a route of administration is the way by which a drug, fluid, poison, or other substance is taken into the body. [1] Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration. Routes can also be classified based ...
The main routes of exposure to carcinogens come from direct contact through the methods of inhalation, contact, injection, absorption or ingestion. [3] Each of these exposure routes and severity of damage can vary depending on the potential carcinogen in question.
Factors that influence chemical toxicity include the dosage, duration of exposure (whether it is acute or chronic), route of exposure, species, age, sex, and environment. Toxicologists are experts on poisons and poisoning. There is a movement for evidence-based toxicology as part of the larger movement towards evidence-based practices.
Along with inhalation, ingestion and injection, dermal absorption is a route of exposure for toxic substances and route of administration for medication. Absorption of substances through the skin depends on a number of factors, the most important of which are concentration , duration of contact, solubility of medication, and physical condition ...
For example, after exposure to DDT, an organochlorine insecticide known to cause problems in the reproductive system, a woman may experience miscarriages, which can be linked to her previous exposure. Biomarkers of exposure are the most widely used because they can provide information on the route, pathway, and sometimes, even the source of ...