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Top: An ancestral gene duplication produces two paralogs (histone H1.1 and 1.2). A speciation event produces orthologs in the two daughter species (human and chimpanzee). Bottom: in a separate species , a gene has a similar function (histone-like nucleoid-structuring protein) but has a separate evolutionary origin and so is an analog.
Multiple sequence alignment (MSA) is the process or the result of sequence alignment of three or more biological sequences, generally protein, DNA, or RNA. These alignments are used to infer evolutionary relationships via phylogenetic analysis and can highlight homologous features between sequences.
Alignments of multiple sequences are used to indicate which regions of each sequence are homologous. [ 40 ] Homologous sequences are orthologous if they are descended from the same ancestral sequence separated by a speciation event: when a species diverges into two separate species, the copies of a single gene in the two resulting species are ...
Homology model of the DHRS7B protein created with Swiss-model and rendered with PyMOL. Homology modeling, also known as comparative modeling of protein, refers to constructing an atomic-resolution model of the "target" protein from its amino acid sequence and an experimental three-dimensional structure of a related homologous protein (the "template").
Top: An ancestral gene duplication produces two paralogs (histone H1.1 and 1.2). A speciation event produces orthologs in the two daughter species (human and chimpanzee). Bottom: in a separate species , a gene has a similar function (histone-like nucleoid-structuring protein) but has a separate evolutionary origin and so is an analog.
A speciation event produces orthologs in the two daughter species (human and chimpanzee). Bottom: in a separate species ( E. coli ), an gene has a similar function ( histone-like nucleoid-structuring protein ) but has a separate evolutionary origin and so is an analog .
However, recent studies using fluorescent labeled Rad51 [11] have indicated that Rad51 fragments elongate via multiple nucleation events followed by growth, with the total fragment terminating when it reaches about 2 μm in length. However, disassociation of Rad51 from dsDNA is slow and incomplete, suggesting that there is a separate mechanism ...
5883 19367 Ensembl ENSG00000172613 ENSMUSG00000024824 UniProt Q99638 Q9Z0F6 RefSeq (mRNA) NM_001243224 NM_004584 NM_011237 RefSeq (protein) NP_001230153 NP_004575 NP_035367 Location (UCSC) Chr 11: 67.32 – 67.4 Mb Chr 19: 4.25 – 4.25 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Cell cycle checkpoint control protein RAD9A is a protein that in humans is encoded by the RAD9A gene ...