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2. Enzalutamide - Wikipedia

   en.wikipedia.org/wiki/Enzalutamide

   Enzalutamide, sold under the brand name Xtandi, is a nonsteroidal antiandrogen (NSAA) medication which is used in the treatment of prostate cancer. [2] [9] It is indicated for use in conjunction with castration in the treatment of metastatic castration-resistant prostate cancer (mCRPC), [2] nonmetastatic castration-resistant prostate cancer, [2] and metastatic castration-sensitive prostate ...

3. Comparison of bicalutamide with other antiandrogens

   en.wikipedia.org/wiki/Comparison_of_bicalutamide...

   Enzalutamide, along with the in-development apalutamide and darolutamide, are newer, second-generation NSAAs. [60] Similarly to bicalutamide and the other first-generation NSAAs , they possess the same core mechanism of action of selective AR antagonism but are thought to bind to the androgen receptor with higher affinity, prevent nuclear ...

4. Medical uses of bicalutamide - Wikipedia

   en.wikipedia.org/wiki/Medical_uses_of_bicalutamide

   Bicalutamide is used primarily in the treatment of early and advanced prostate cancer. [1] It is approved at a dosage of 50 mg/day as a combination therapy with a gonadotropin-releasing hormone analogue (GnRH analogue) or orchiectomy (that is, surgical or medical castration) in the treatment of stage D2 metastatic prostate cancer (mPC), [2] [3] and as a monotherapy at a dosage of 150 mg/day ...

5. How to Finally Address Your Stress in the New Year - AOL

   www.aol.com/finally-address-stress-125700280.html

   Ulcerative colitis (long-term inflammatory bowel disease) Immune disorders If your stress feels unmanageable or like it’s affecting your overall health, reach out to a healthcare professional ...

6. Are doctors overtreating early-stage breast cancer? Is active ...

   www.aol.com/doctors-overtreating-early-stage...

   Often called “stage-zero breast cancer” or “precancer,” the Breast Cancer Research Foundation reports a 98% survival rate after 10 years. ... "We need that long-term follow-up before we ...

7. Side effects of bicalutamide - Wikipedia

   en.wikipedia.org/wiki/Side_effects_of_bicalutamide

   This was shown in the SPCG-6 Tooltip Scandinavian Prostate Cancer Group 6 substudy (n=1218) of the EPC programme, in which overall survival was significantly worse in the 150 mg/day bicalutamide monotherapy group compared to the placebo/standard care group (HR Tooltip hazard ratio = 1.47; 95% CI Tooltip confidence interval = 1.06–2.03). [81]

8. Baby Has $5 Million Surgery to Remove Left Side of Brain at ...

   www.aol.com/lifestyle/baby-5-million-surgery...

   Related: Mom Noticed Her Toddler Was Acting Strange.Days Later, She Found Out It Was Stage 4 Cancer (Exclusive) From there, things began to get worse. Andalusia recalls seeing Caper’s eye twitch ...

9. Discovery and development of antiandrogens - Wikipedia

   en.wikipedia.org/wiki/Discovery_and_development...

   This suggests that long term use of these antiandrogens during prostate cancer can lead to the development of androgen-independent prostate cancer cells or the ability of adrenal androgens to support tumor growth. [8] This phenomenon is called antiandrogen withdrawal syndrome (AWS) and is one of the major drawbacks of existing antiandrogens ...