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[193] [194] As much as 90% of testosterone is converted into 5α-DHT in so-called androgenic tissues with high 5α-reductase expression, [184] and due to the several-fold greater potency of 5α-DHT as an AR agonist relative to testosterone, [195] it has been estimated that the effects of testosterone are potentiated 2- to 3-fold in such tissues.
Testicular atrophy is a medical condition in which one or both testicles (or "testes") diminish in size and may be accompanied by reduced testicular function. Testicular atrophy is not related to the temporary shrinkage of the surrounding scrotum, which might occur in response to cold temperature. As the testicles are involved in testosterone ...
A 2017 review and meta-analysis found sperm counts among Western men (i.e. men in Australia, Europe, New Zealand, and North America) declined 50–60% between 1973 and 2011, with an average decline of 1.4% per year.
[173] [174] In men, a study found that treatment with a relatively low dosage of 20 μg/day ethinylestradiol for 5 weeks increased circulating SHBG levels by 150% and, due to the accompanying decrease free testosterone levels, increased total circulating levels of testosterone by 50% (via reduced negative feedback by androgens on the HPG axis).
According to the Mayo Clinic, "[H]ormone testosterone may boost sex drive for some women after menopause.But there's little research on how safe it is and how well it works over the long term. It ...
A 1992 World Health Organization report described normal human semen as having a volume of 2 mL or greater, pH of 7.2 to 8.0, sperm concentration of 20×10 6 spermatozoa/mL or more, sperm count of 40×10 6 spermatozoa per ejaculate or more, and motility of 50% or more with forward progression (categories a and b) of 25% or more with rapid ...
At the conclusion of its sixth rate-setting policy meeting of 2024 on September 18, 2024, the Federal Reserve announced it was lowering the federal funds target interest rate by 50 basis points to ...
Financial concerns are a fact of life for America's retirees. In fact, an AARP survey found that 20% of adults ages 50+ have no retirement savings, and more than half (61%) are worried they will ...
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