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  2. Depression (mood) - Wikipedia

    en.wikipedia.org/wiki/Depression_(mood)

    Emotions. v. t. e. Depression is a mental state of low mood and aversion to activity. [3] It affects about 3.5% of the global population, or about 280 million people of all ages (as of 2020). [4] Depression affects a person's thoughts, behavior, feelings, and sense of well-being. [5]

  3. Major depressive disorder - Wikipedia

    en.wikipedia.org/wiki/Major_depressive_disorder

    Major depressive disorder (MDD), also known as clinical depression, is a mental disorder [ 9 ] characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. Introduced by a group of US clinicians in the mid-1970s, [ 10 ] the term was adopted by the American ...

  4. Depression in childhood and adolescence - Wikipedia

    en.wikipedia.org/wiki/Depression_in_childhood...

    Base rates and prevalence. About 8% of children and adolescents suffer from depression. [7] In 2016, 51% of students (teens) who visited a counseling center reported having anxiety, followed by depression (41%), relationship concerns (34%) and suicidal ideation (20.5%). [8] Many students reported experiencing multiple conditions at once.

  5. Mood disorder - Wikipedia

    en.wikipedia.org/wiki/Mood_disorder

    Depressive disorder (also known as depression) is a common mental disorder. It involves a depressed mood or loss of pleasure or interest in activities for long periods of time. Depression is different from regular mood changes and feelings about everyday life. It can affect all aspects of life.

  6. History of depression - Wikipedia

    en.wikipedia.org/wiki/History_of_depression

    In the mid-20th century, researchers theorized that depression was caused by a chemical imbalance in neurotransmitters in the brain, a theory based on observations made in the 1950s of the effects of reserpine and isoniazid in altering monoamine neurotransmitter levels and affecting depressive symptoms. [32]

  7. Biology of depression - Wikipedia

    en.wikipedia.org/wiki/Biology_of_depression

    Biology of depression. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD), [ 1 ] and this has encouraged advocates of various theories that seek to identify a biochemical origin of the disease, as opposed to theories that emphasize psychological or situational causes.

  8. Major depressive episode - Wikipedia

    en.wikipedia.org/wiki/Major_depressive_episode

    Antidepressants. A major depressive episode (MDE) is a period characterized by symptoms of major depressive disorder. Those affected primarily exhibit a depressive mood for at least two weeks or more, and a loss of interest or pleasure in everyday activities. Other symptoms can include feelings of emptiness, hopelessness, anxiety, worthlessness ...

  9. Depressive personality disorder - Wikipedia

    en.wikipedia.org/wiki/Depressive_personality...

    The DSM-IV defines depressive personality disorder as "a pervasive pattern of depressive cognitions and behaviors beginning by early adulthood and occurring in a variety of contexts." Depressive personality disorder occurs independently of major depressive episodes, making it a distinct diagnosis not included in the definition of either major ...

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