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Gadoteric acid, sold under the brand name Dotarem among others, is a macrocycle -structured gadolinium-based MRI contrast agent (GBCA). It consists of the organic acid DOTA as a chelating agent, and gadolinium (Gd 3+), and is used in form of the meglumine salt (gadoterate meglumine). [4][5] The paramagnetic property of gadoteric acid reduces ...
This iron based contrast agent was never commercially launched and its development was discontinued in early 2000s due to safety concerns. [54] In 2017 GE Healthcare launched a macrocyclic extracellular gadolinium based contrast agent containing gadoteric acid as gadoterate meglumine under the trade name Clariscan. [55]
Gadoxetic acid is a gadolinium-based MRI contrast agent. [ 4 ] Its salt, gadoxetate disodium, is marketed as Primovist in Europe and Eovist in the United States by Bayer HealthCare Pharmaceuticals. [ 2 ][ 5 ]
Gadopiclenol. Gadopiclenol, sold under the brand name Elucirem among others, is a contrast agent used with magnetic resonance imaging (MRI) to detect and visualize lesions with abnormal vascularity in the central nervous system and in the body. [2][7] Gadopiclenol is a paramagnetic macrocyclic non-ionic complex of gadolinium.
A contrast agent(or contrast medium) is a substanceused to increase the contrastof structures or fluids within the body in medical imaging.[1] Contrast agents absorb or alter external electromagnetismor ultrasound, which is different from radiopharmaceuticals, which emit radiationthemselves. In X-rayimaging, contrast agents enhance the ...
Medical uses. Gadobutrol is a medicinal product used in diagnostic magnetic resonance imaging (MRI) in adults and children. It provides contrast enhancement during cranial, spinal, breast, or other investigations. In the central nervous system, Gadobutrol works by highlighting any areas with disrupted blood brain barrier (BBB) and/or abnormal ...
Pages in category "MRI contrast agents" The following 15 pages are in this category, out of 15 total. ... Gadoteric acid; Gadoteridol; Gadoversetamide; Gadoxetic acid ...
Iodinated contrast contains iodine.It is the main type of radiocontrast used for intravenous administration.Iodine has a particular advantage as a contrast agent for radiography because its innermost electron ("k-shell") binding energy is 33.2 keV, similar to the average energy of x-rays used in diagnostic radiography.