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Calorie restriction (also known as caloric restriction or energy restriction) is a dietary regimen that reduces the energy intake from foods and beverages without incurring malnutrition. [1][2] The possible effect of calorie restriction on body weight management, longevity, and aging-associated diseases has been an active area of research. [1]
The free radical theory of aging states that organisms age because cells accumulate free radical damage over time. [ 1 ] A free radical is any atom or molecule that has a single unpaired electron in an outer shell. [ 2 ] While a few free radicals such as melanin are not chemically reactive, most biologically relevant free radicals are highly ...
The hallmarks of aging are the types of biochemical changes that occur in all organisms that experience biological aging and lead to a progressive loss of physiological integrity, impaired function and, eventually, death. They were first listed in a landmark paper in 2013 [1] to conceptualize the essence of biological aging and its underlying ...
These lifestyle factors may support cellular health by preventing methylation, which can influence gene expression. Experts say the best way to adopt Life’s Essential 8 behaviors is by taking ...
A new review of the existing evidence shows how dietary interventions like keto, the Mediterranean diet, or intermittent fasting can help promote healthy aging and keep disease at bay.
These findings were independent, in that more sugar meant more accelerated biological age, even if a woman's overall diet was healthier, but sticking to a healthier overall diet was associated ...
Aubrey David Nicholas Jasper de Grey (/ dəˈɡreɪ /; born 20 April 1963) is an English biomedical gerontologist. He is the author of The Mitochondrial Free Radical Theory of Aging (1999) and co-author of Ending Aging (2007). De Grey is known for his view that medical technology may enable human beings alive today not to die from age-related ...
All it takes, he believes, is new technology—yet to be created—that can eliminate aging at the cellular level, repair DNA, and reprogram cells for a drastically different aging process.