Search results
Results from the WOW.Com Content Network
Phoebus Aaron Theodore Levene(25 February 1869 – 6 September 1940) was a Russian-born American biochemistwho studied the structure and function of nucleic acids. He characterized the different forms of nucleic acid, DNAfrom RNA, and found that DNA contained adenine, guanine, thymine, cytosine, deoxyribose, and a phosphate group.
The tetranucleotide hypothesis of Phoebus Levene [1] proposed that DNA was composed of repeating sequences of four nucleotides. [2] It was very influential for three decades, and was developed by Levene at least into the 1910, and the diagram at the right illustrates the view of Levene and Tipson. [3] In 1940, at the time of Levene's death ...
In the early twentieth century, biologists thought that proteins carried genetic information. This was based on the belief that proteins were more complex than DNA. Phoebus Levene's influential "tetranucleotide hypothesis", which incorrectly proposed that DNA was a repeating set of identical nucleotides, supported this
According to Phoebus Levene's influential "tetranucleotide hypothesis", DNA consisted of repeating units of the four nucleotide bases and had little biological specificity. DNA was therefore thought to be the structural component of chromosomes, whereas the genes were thought likely to be made of the protein component of chromosomes.
t. e. " Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid " was the first article published to describe the discovery of the double helix structure of DNA, using X-ray diffraction and the mathematics of a helix transform. It was published by Francis Crick and James D. Watson in the scientific journal Nature on pages ...
This strongly hinted towards the base pair makeup of the DNA, although Chargaff did not explicitly state this connection himself. For this research, Chargaff is credited with disproving the tetranucleotide hypothesis [14] (Phoebus Levene's widely accepted hypothesis that DNA was composed of a large number of repeats of GACT). Most researchers ...
Another notable contributor to the DNA model was Phoebus Levene, who proposed the "polynucleotide model" of DNA in 1919 as a result of his biochemical experiments on yeast. [17] In 1950, Erwin Chargaff expanded on the work of Levene and elucidated a few critical properties of nucleic acids: first, the sequence of nucleic acids varies across ...
The DNA model shown (far right) is a space-filling, or CPK, model of the DNA double helix. Animated molecular models, such as the wire, or skeletal, type shown at the top of this article, allow one to visually explore the three-dimensional (3D) structure of DNA. Another type of DNA model is the space-filling, or CPK, model.