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Specialty. Rheumatology. Diffuse idiopathic skeletal hyperostosis (DISH) is a condition characterized by abnormal calcification/bone formation (hyperostosis) of the soft tissues surrounding the joints of the spine, and also of the peripheral or appendicular skeleton. [ 1 ] In the spine, there is bone formation along the anterior longitudinal ...
Specialty. Rheumatology. Hypertrophic osteoarthropathy is a medical condition combining clubbing and periostitis of the small hand joints, especially the distal interphalangeal joints and the metacarpophalangeal joints. Distal expansion of the long bones as well as painful, swollen joints [3] and synovial villous proliferation are often seen.
Other possible pulmonary manifestations of MFS include sleep apnea [25] and idiopathic obstructive lung disease. [26] Pathologic changes in the lungs have been described such as cystic changes, emphysema , pneumonia , bronchiectasis , bullae , apical fibrosis and congenital malformations such as middle lobe hypoplasia.
H&E stain. Fibrous dysplasia is a very rare [2] nonhereditary genetic disorder where normal bone and marrow is replaced with fibrous tissue, resulting in formation of bone that is weak and prone to expansion. As a result, most complications result from fracture, deformity, functional impairment, pain, and the impingement of nerves. [3]
Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodelling and the formation of permanent scar tissue. [1][2] Repeated injuries, chronic inflammation and repair are susceptible to ...
Pott's disease, or Pott disease, named for British surgeon Percivall Pott who first described the symptoms in 1799, [ 1 ] is tuberculosis of the spine, [ 2 ][ 3 ] usually due to haematogenous spread from other sites, often the lungs. The lower thoracic and upper lumbar vertebrae areas of the spine are most often affected.
15% (50 year olds), 70% (over 80 year olds)[7] Osteoporosisis a systemic skeletal disorder characterized by low bone mass, micro-architectural deterioration of bone tissueleading to more porous bone, and consequent increase in fracturerisk. It is the most common reason for a broken bone among the elderly.[3]
Fibrodysplasia ossificans progressiva (/ ˌ f aɪ b r oʊ d ɪ ˈ s p l eɪ ʒ (i) ə ɒ ˈ s ɪ f ɪ k æ n z p r ə ˈ ɡ r ɛ s ɪ v ə /; [1] abbr. FOP), also called Münchmeyer disease or formerly myositis ossificans progressiva, is an extremely rare connective tissue disease in which fibrous connective tissue such as muscle, tendons, and ligaments turn into bone tissue (ossification).