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Tissue nanotransfection (TNT) is an electroporation-based technique capable of gene and drug cargo delivery or transfection at the nanoscale. Furthermore, TNT is a scaffold-less tissue engineering (TE) technique that can be considered cell-only or tissue inducing depending on cellular or tissue level applications. The transfection method makes ...
Nano-scaffolds along with cells and growth factor signals are utilized in tissue engineering applications. [9] Tissue engineering applications are designed to overcome hurdles associated with allotransplantation, which include unavailable donors, complex surgeries, and postoperative care. [10] In 2015, the tissue engineering global market was ...
Nanofabrics research is an interdisciplinary effort involving bioengineering, [5] molecular chemistry, physics, electrical engineering, computer science, and systems engineering. [3] Applications of nanofabrics have the potential to revolutionize textile manufacturing [6] and areas of medicine such as drug delivery and tissue engineering. [7]
Nanotechnology may be used as part of tissue engineering to help reproduce, repair, or reshape damaged tissue using suitable nanomaterial-based scaffolds and growth factors. If successful, tissue engineering if successful may replace conventional treatments like organ transplants or artificial implants.
Nanotechnology may play role in tissue engineering. When designing scaffolds, researchers attempt to mimic the nanoscale features of a cell's microenvironment to direct its differentiation down a suitable lineage. [68] For example, when creating scaffolds to support bone growth, researchers may mimic osteoclast resorption pits. [69]
For example, DNA nanotechnology or cellular engineering would be classified as bionanotechnology because they involve working with biomolecules on the nanoscale. Conversely, many new medical technologies involving nanoparticles as delivery systems or as sensors would be examples of nanobiotechnology since they involve using nanotechnology to ...
Micro-mass cultures of C3H-10T1/2 cells at varied oxygen tensions stained with Alcian blue. A commonly applied definition of tissue engineering, as stated by Langer [3] and Vacanti, [4] is "an interdisciplinary field that applies the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain, or improve [Biological tissue] function or a ...
A range of polymeric nanocomposites are used for biomedical applications such as tissue engineering, drug delivery, cellular therapies. [29] [30] Due to unique interactions between polymer and nanoparticles, a range of property combinations can be engineered to mimic native tissue structure and properties. A range of natural and synthetic ...