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Blood pressure is classified by two measurements, the systolic (first number) and diastolic (second number) pressures. [1] For most adults, normal blood pressure at rest is within the range of 100–140 millimeters mercury (mmHg) systolic and 60–90 mmHg diastolic.
The renin–angiotensin system was known to play an important role in blood pressure regulation, and angiotensin converting enzyme (ACE) inhibitors were developed through rational drug design. In 1977 captopril, an orally active agent, was described; [35] this led to the development of a number of other ACE inhibitors. [21]
Reference ranges for blood pressure (BP) in children [29] Stage Approximate age Systolic BP, mmHg Diastolic BP, mmHg Infants 0–12 months: 75–100: 50–70 Toddlers and preschoolers 1–5 years: 80–110: 50–80 School age 6–12 years: 85–120: 50–80 Adolescents 13–18 years: 95–140: 60–90
Regarding ideal numbers, the famous M.D. says: "Your blood pressure is supposed to be under 140 over 90, optimally closer to 120 over 80."
The standard definition of a reference range for a particular measurement is defined as the interval between which 95% of values of a reference population fall into, in such a way that 2.5% of the time a value will be less than the lower limit of this interval, and 2.5% of the time it will be larger than the upper limit of this interval, whatever the distribution of these values.
A minimum systolic value can be roughly estimated by palpation, most often used in emergency situations, but should be used with caution. [10] It has been estimated that, using 50% percentiles, carotid, femoral and radial pulses are present in patients with a systolic blood pressure > 70 mmHg, carotid and femoral pulses alone in patients with systolic blood pressure of > 50 mmHg, and only a ...
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