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Autoimmune inner ear disease (AIED) was first defined by Dr. Brian McCabe in a landmark paper describing an autoimmune loss of hearing. [2] The disease results in progressive sensorineural hearing loss (SNHL) that acts bilaterally and asymmetrically, and sometimes affects an individual's vestibular system .
Treatment with anakinra, an interleukin 1 receptor antagonist, can lead to an improvement in the hearing loss. [3] Rilonacept (Arcalyst) a dimeric fusion protein for the treatment of CAPS. Canakinumab, a monoclonal antibody against interleukin-1β
Susac's syndrome (retinocochleocerebral vasculopathy) is a very rare form of microangiopathy characterized by encephalopathy, branch retinal artery occlusions and hearing loss. [1] The cause is unknown but it is theorized that antibodies are produced against endothelial cells in tiny arteries which leads to damage and the symptoms related to ...
Whole-person specialty care, a model where a comprehensive care team works together to coordinate personalized and individualized treatment, is offering renewed hope for patients.
The technology can uniquely identify a person by analyzing the antibodies in body fluids. A unique, individual set of antibodies, called individual specific autoantibodies (ISA), is found in blood, serum, saliva, urine, semen, perspiration, tears, and body tissues, and the antibodies are not affected by illness, medication, or food/drug intake.
Ashton Kutcher said he lost his ability to walk and see for nearly a year after being diagnosed with vasculitis. Vasculitis is an autoimmune disorder caused by inflammation to blood vessels.
Patients often have cartilage-specific antibodies present during acute relapsing polychondritis episodes. Antinuclear antibody reflexive panel, rheumatoid factor, and antiphospholipid antibodies are tests that may assist in the evaluation and diagnosis of autoimmune connective-tissue diseases. [citation needed]
Ashton Kutcher is "lucky to be alive" after dealing with a rare autoimmune disorder two years ago that left him unable to hear, see or walk. The That '70s Show alum opens up about his health ...
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