Search results
Results from the WOW.Com Content Network
Atezolizumab, sold under the brand name Tecentriq among others, is a monoclonal antibody medication used to treat urothelial carcinoma, non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC), hepatocellular carcinoma and alveolar soft part sarcoma, [9] [11] but discontinued for use in triple-negative breast cancer (TNBC). [12]
The subcutaneous injection of atezolizumab and hyaluronidase was evaluated in IMscin001 (NCT03735121), an open-label, multi-center, international, randomized trial in adults with locally advanced or metastatic non-small cell lung cancer who were not previously exposed to cancer immunotherapy and who had disease progression following treatment with platinum-based chemotherapy. [2]
Atezolizumab (Tecentriq) is a fully humanised IgG1 (immunoglobulin 1) antibody developed by Roche Genentech. In 2016, the FDA approved atezolizumab for urothelial carcinoma and non-small cell lung cancer. Avelumab (Bavencio) is a fully human IgG1 antibody developed by Merck Serono and Pfizer.
Median OS was 19.8 and 14.9 months for patients treated with chemotherapy plus Bevacizumab, with or without atezolizumab, respectively. [61] [60] [16] Median OS with Atezolizumab and chemotherapy alone was 19.5 months, [60] raising question with regard to the added value of Bevacizumab to this combination for the general patients population. [16]
The first checkpoint antibody approved by the FDA was ipilimumab, approved in 2011 for treatment of melanoma. [2] It blocks the immune checkpoint molecule CTLA-4.Clinical trials have also shown some benefits of anti-CTLA-4 therapy on lung cancer or pancreatic cancer, specifically in combination with other drugs.
Iron Man (TV series) (Njeriu i hekurt) Jackie Chan Adventures (Aventurat e Xheki Çan) Jason and the Heroes of Mount Olympus (Xhejsoni dhe heronjtë e malit Olimp) [88] Jelly Jamm (Planeti i muzikës) Jin Jin and the Panda Patrol (Xhin Xhini) [89] Julius Jr. (Xhuliusi i vogël) [90] Jurassic World Camp Cretaceous (Bota Xhurasik: Aventura të reja)
Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Atezolizumab. PubMed provides review articles from the past five years (limit to free review articles)
IN TV; Supersonic TV; BBF TV; Folk Plus; TV Blue Sky; Tirana TV; Club TV; MusicAL; Click TV; STV Folk; Albsat Music; ALB Music HD; ALB Hits HD; ALB Koncert HD; ALB Folk HD; ALB Çifteli HD; ALB Hip Hop HD; Globe Music; Real TV; City TV; 3+ HD