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Methylphosphonyl dichloride (DC) or dichloro is an organophosphorus compound. It has commercial application in oligonucleotide synthesis, [1] but is most notable as being a precursor to several chemical weapons agents. It is a white crystalline solid that melts slightly above room temperature. [2]
Methyldichlorophosphine belongs to the group of halophosphines, some of which are used as intermediates in the production of plant protection agents, stabilizers for plastics, and catalysts.
Methylphosphonic acid is an organophosphorus compound with the chemical formula CH 3 P(O)(OH) 2.The phosphorus center is tetrahedral and is bonded to a methyl group, two OH groups and an oxygen.
Methylphosphonic dichloride and triethylamine are dissolved in benzene. 3,3,5-Trimethylcyclohexanol is then slowly added while stirring and cooling. The reaction temperature is maintained at 10-15 °C. The mixture is then heated to 40 °C for 1 hour. A benzene solution of 3,3,5-trimethylcyclohexyl methylphosphonochloridate is formed.
Dimethyl methylphosphonate can be prepared from trimethyl phosphite and a halomethane (e.g. iodomethane) via the Michaelis–Arbuzov reaction. [2]Dimethyl methylphosphonate is a schedule 2 chemical as it may be used in the production of chemical weapons.
[1] [2] However, aluminum chloride often induces diarylation; a cleaner catalyst for monoarylation is stannic chloride. [2] The compound is an intermediate for the synthesis of other chemicals for instance dimethylphenylphosphine: C 6 H 5 PCl 2 + 2 CH 3 MgI → C 6 H 5 P(CH 3) 2 + 2 MgICl. Many tertiary phosphines can be prepared by this route. [3]
87 °C (189 °F; 360 K) [1] at 4 mmHg Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references
GV (IUPAC name: 2-(Dimethylamino)ethyl N,N-dimethylphosphoramidofluoridate), also known as EA-5365 and GP (USACC cryptonym), is an organophosphate nerve agent.GV is a ...