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It is also possible that NS5A is a critical component during HCV replication and subcellular localization, which may shed light on the poorly understood HCV life cycle. [ 1 ] [ 4 ] Additionally, NS5A has been shown to modulate the polymerase activity of NS5B , an RNA-dependent RNA polymerase (RdRp) . [ 3 ]
HCV genome. Nonstructural protein 5B (NS5B) is a viral protein found in the hepatitis C virus (HCV). [1] It is an RNA-dependent RNA polymerase, having the key function of replicating HCV's viral RNA by using the viral positive RNA strand as a template to catalyze the polymerization of ribonucleoside triphosphates (rNTP) during RNA replication.
HCV genome. Nonstructural protein 3 (NS3), also known as p-70, is a viral nonstructural protein that is 70 kDa cleavage product of the hepatitis C virus polyprotein. It acts as a serine protease. [1] [2] C-terminal two-thirds of the protein also acts as helicase and nucleoside triphosphatase. [3]
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There are several diagnostic tests for hepatitis C, including HCV antibody enzyme immunoassay (ELISA), recombinant immunoblot assay, and quantitative HCV RNA polymerase chain reaction (PCR). [16] HCV RNA can be detected by PCR typically one to two weeks after infection. In contrast, antibodies can take substantially longer to form and thus be ...
The hepatitis C virus (HCV) [3] is a small (55–65 nm in size), enveloped, positive-sense single-stranded RNA virus of the family Flaviviridae. The hepatitis C virus is the cause of hepatitis C and some cancers such as liver cancer ( hepatocellular carcinoma , abbreviated HCC) and lymphomas in humans.
Qualitative detection of HIV-1 RNA and hepatitis C virus (HCV) RNA from volunteer donors of whole blood and blood components, screen of live organ donors, and test blood specimens to screen cadaveric donors. HBV screening of individual samples and pooled samples. 10/3/2006: Gen-Probe San Diego, CA US Licence 1592 Chiron Corporation
The Vatican says it is unclear how long Pope Francis will stay in hospital after he was admitted on Friday with a respiratory tract infection.. The 88-year-old pope’s current condition was ...
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