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Proton-pump inhibitors (PPIs) are a class of medications that cause a profound and prolonged reduction of stomach acid production. They do so by irreversibly inhibiting the stomach's H + /K + ATPase proton pump . [ 1 ]
The oral bioavailability of PPIs is high; 77% for pantoprazole, 80–90% for lansoprazole and 89% for esomeprazole. All the PPIs except tenatoprazole are rapidly metabolized in the liver by CYP enzymes, mostly by CYP2C19 and CYP3A4. PPIs are sensitive to CYP enzymes and have different pharmacokinetic profiles.
PPIS handles phytosanitary matters both within Israel and in foreign trade. In pursuit of that purpose, it operates offices both within the country [ 2 ] and in its foreign embassies, [ 3 ] [ 4 ] and acts as representative to some international bodies such as the IPPC ( International Plant Protection Convention ) [ 1 ] and the EPPO ( European ...
Pantoprazole, sold under the brand name Protonix, among others, is a medication used for the treatment of stomach ulcers, short-term treatment of erosive esophagitis due to gastroesophageal reflux disease (GERD), maintenance of healing of erosive esophagitis, and pathological hypersecretory conditions including Zollinger–Ellison syndrome.
The Progressive Policy Institute (PPI) is a non-profit, 501(c)(3) organization that serves as a public policy think tank in the United States. The Democratic Leadership Council (DLC) founded it in 1989. [1] The Washington Post has described it as "a centrist Democratic institution." [2]
The Young Women Muslim Association of Singapore (YWMA), more commonly known as Persatuan Pemudi Islam Singapura (PPIS) (in Malay), is the oldest Muslim women organization in the world, and a household name for the Muslim community in Singapore. It is a voluntary welfare organization and has official charity status in Singapore.
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Pirate Parties International (PPI) is an international non-profit and non-governmental organization with headquarters in Brussels, Belgium. [1] Formed in 2010, it serves as a worldwide organization for Pirate Parties , currently representing 39 members from 36 countries across Europe , the Americas , Asia , Africa and Australasia .