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The history of syphilis has been well studied, but the exact origin of the disease remains unknown. [3] It appears to have originated in both Africa and America. [4] [5] As such, there are two primary hypotheses: one proposes that syphilis was carried to Europe from the Americas by the crew(s) of Christopher Columbus as a byproduct of the Columbian exchange, while the other proposes that ...
Treatment at this stage solely limits further progression of the disease and has a limited effect on damage which has already occurred. [3] Serologic cure can be measured when the non-treponemal titers decline by a factor of 4 or more in 6–12 months in early syphilis or 12–24 months in late syphilis. [21]
In the early 1870s, Ehrlich's cousin Karl Weigert was the first person to stain bacteria with dyes and to introduce aniline pigments for histological studies and bacterial diagnostics. During his studies in Strassburg under the anatomist Heinrich Wilhelm Waldeyer , Ehrlich continued the research started by his cousin in pigments and staining ...
Without treatment, syphilis can cause physical disfigurement, blindness and mental impairment. As a sexually transmitted disease, it has long carried a stigma — hence the past attempts by ...
Man with syphilis in German East Africa, c. early 1900s. Syphilis, a sexually transmitted infection, is a major danger to public health, particularly in developing countries, including those in sub-Saharan Africa. The disease, whose origin is contested amongst researchers, arrived in Africa no later than the 16th century. Since then, it has ...
Hinton developed a flocculation test for syphilis in 1927, and co-developed another syphilis test using spinal fluid with a colleague that would come to be known as the Davies-Hinton test. These tests were considered a boon for medicine, as the treatment for syphilis at the time was long, painful, and hazardous.
In another hopeful development, a shortage that began in early 2023 of the only recommended treatment for syphilis among pregnant women, Pfizer’s Bicillin-LA, has abated.
Inside were documents telling a tale that, even today, staggers the imagination: For four decades, the U.S. government had denied hundreds of poor Black men treatment for syphilis so researchers ...
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