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The Biopython project is an open-source collection of non-commercial Python tools for computational biology and bioinformatics, created by an international association of developers. [1] [4] [5] It contains classes to represent biological sequences and sequence annotations, and it is able to read and write to a variety of file formats.
Open Bioinformatics Foundation: Biopython: Python language toolkit Cross-platform: Biopython [2] Open Bioinformatics Foundation: BioRuby: Ruby language toolkit Linux, macOS, Windows [3] GPL v2 or Ruby: Open Bioinformatics Foundation: BLAST: Algorithm and program for comparing primary biological sequence information, including DNA and protein ...
Galaxy is open-source software implemented using the Python programming language. It is developed by the Galaxy team [23] at Penn State, Johns Hopkins University, Oregon Health & Science University, and the Galaxy Community. [24] Galaxy is extensible, as new command line tools can be integrated and shared within the Galaxy ToolShed. [25]
The BLOSUM62 matrix, the amino acids have been grouped and coloured based on Margaret Dayhoff's classification scheme. Positive and zero values have been highlighted. In bioinformatics, the BLOSUM (BLOcks SUbstitution Matrix) matrix is a substitution matrix used for sequence alignment of proteins.
GenePattern is a freely available computational biology open-source software package originally created and developed at the Broad Institute for the analysis of genomic data. . Designed to enable researchers to develop, capture, and reproduce genomic analysis methodologies, GenePattern was first released in 20
A Python library for the probabilistic sampling of RNA structures that are compatible with a given nucleotide sequence and that are RNA-like on a local length scale. Yes: sourcecode [42] FARFAR2: Automated de novo prediction of native-like RNA tertiary structures . Yes: webserver [43] iFoldRNA: three-dimensional RNA structure prediction and ...
Rosalind is an educational resource and web project for learning bioinformatics through problem solving and computer programming. [1] [2] [3] Rosalind users learn bioinformatics concepts through a problem tree that builds up biological, algorithmic, and programming knowledge concurrently or learn by topics, with the topic of Alignment, Combinatorics, Computational Mass Spectrometry, Heredity ...
BLAST is one of the most widely used bioinformatics programs for sequence searching. [4] It addresses a fundamental problem in bioinformatics research. The heuristic algorithm it uses is much faster than other approaches, such as calculating an optimal alignment. This emphasis on speed is vital to making the algorithm practical on the huge ...