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Generally, diseases outlined within the ICD-10 codes L80-L81 within Chapter XII: Diseases of the skin and subcutaneous tissue should be included in this category. Disturbances of human pigmentation, either loss or reduction, may be related to loss of melanocytes or the inability of melanocytes to produce melanin or transport melanosomes correctly.
Cross syndrome (also known as "Cross–McKusick–Breen syndrome", "hypopigmentation and microphthalmia", and "oculocerebral-hypopigmentation syndrome") is an extremely rare disorder characterized by white skin, blond hair with yellow-gray metallic sheen, small eyes with cloudy corneas, jerky nystagmus, gingival fibromatosis and severe intellectual disability and physical retardation.
Hypopigmentation can be caused by hereditary conditions such as vitiligo, melasma, pityriasis versicolor, pityriasis alba, albinism, and fungal infections. [ 4 ] Hyperpigmentation results from an increase in melanin synthesis, which is mostly brought on by sun exposure, dermatological disorders, hormones, aging, genetic factors, skin injuries ...
Hypopigmentation is characterized specifically as an area of skin becoming lighter than the baseline skin color, but not completely devoid of pigment. This is not to be confused with depigmentation , which is characterized as the absence of all pigment. [ 1 ]
Postinflammatory hypopigmentation is a highly prevalent pigmentary disease. It can happen to any type of skin. Nonetheless, individuals with darker skin seem to have it more frequently and visibly, perhaps due to the color contrast with their natural skin. The incidence of postinflammatory hypopigmentation is the same for both sexes. [2]
Griscelli syndrome is defined by the characteristic hypopigmentation, with frequent pyogenic infection, enlargement of the liver and spleen, a low blood neutrophil level, low blood platelet level, and immunodeficiency. Very often there is also impaired natural killer cell activity, absent delayed-type hypersensitivity and a poor cell ...
Hyperchromia can refer to hyperpigmentation, [2] and hypochromia can refer to hypopigmentation. [ 3 ] Dyschromatoses involve both hyperpigmented and hypopigmented macules.
Download QR code; Print/export Download as PDF ... Griscelli syndrome type 3 is a disorder of melanosome transport presenting initially with hypopigmentation. [1 ...