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The smallpox vaccine is used to prevent smallpox infection caused by the variola virus. [10] It is the first vaccine to have been developed against a contagious disease. In 1796, British physician Edward Jenner demonstrated that an infection with the relatively mild cowpox virus conferred immunity against the deadly smallpox virus.
A few days after Mumdžić's death, 140 smallpox cases erupted across Kosovo province. [10] On 16 March, the smallpox virus was isolated in Belgrade by Ana Gligić, the head of the national smallpox laboratory, which was followed by strict measures that prevented the spread of the disease in the city and thus a major disaster. [11] [12]
In 1849 nearly 13% of all Calcutta deaths were due to smallpox. [32] Between 1868 and 1907, there were approximately 4.7 million deaths from smallpox in India. Between 1926 and 1930, there were 979,738 cases of smallpox with a mortality of 42.3%. [33]
Smallpox was an infectious disease caused by variola virus (often called smallpox virus), which belongs to the genus Orthopoxvirus. [7] [11] The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, [10] making smallpox the only human disease to have been eradicated to date.
The use of Jenner's new vaccine spread rapidly through Europe and had a significant positive impact on the severity and frequency of smallpox epidemics. [1] [4] The vaccine first reached Spain in late 1800 and by the end of 1801, several thousand persons had been vaccinated across the country. The efforts were well publicised in Spain and by ...
Fauci stated, "New York City, in March and April 1947, vaccinated 6,350,000 people; 5 million of which they did in two weeks. I was a six-year-old boy who was one of those who got vaccinated. So if New York City can do 5 million in two weeks, the United States could do a million a day. We can do it." [22]
Regional groups like the European Commission said they would donate 215,000 vaccine doses ... on its smallpox vaccine, similar to the one used for mpox, back in 2003 with the U.S. government ...
This is a timeline of the development of prophylactic human vaccines. Early vaccines may be listed by the first year of development or testing, but later entries usually show the year the vaccine finished trials and became available on the market. Although vaccines exist for the diseases listed below, only smallpox has