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In the pharmaceutical industry, drug dissolution testing is routinely used to provide critical in vitro drug release information for both quality control purposes, i.e., to assess batch-to-batch consistency of solid oral dosage forms such as tablets, and drug development, i.e., to predict in vivo drug release profiles. [1]
A simplified version of the Emerson soil dispersion test [3] can be completed in the field on a 20-minute to two-hour timescale. Laboratory tests used to diagnose a soil as dispersive focus on the cation exchange capacity of a soil sample and its cation breakdown. Soil cations are dominated by Ca 2+, Mg 2+, K +, and Na +, as well as H + in ...
In pharmaceutics, sink condition is a term mostly related to the dissolution testing procedure.. It means using a sheer volume of solvent, usually about 5 to 10 times greater than the volume present in the saturated solution of the targeted chemical (often the API, and sometimes the excipients) contained in the dosage form being tested.
A soil test is a laboratory or in-situ analysis to determine the chemical, physical or biological characteristics of a soil. Possibly the most widely conducted soil tests are those performed to estimate the plant-available concentrations of nutrients in order to provide fertilizer recommendations in agriculture.
Effervescent or carbon tablets are tablets which are designed to dissolve in water and release carbon dioxide. The carbon dioxide is generated by a reaction of a compound containing bicarbonate, such as sodium bicarbonate or magnesium bicarbonate, with an acid such as citric acid or tartaric acid. Both compounds are present in the tablet in ...
Soil quality reflects how well a soil performs the functions of maintaining biodiversity and productivity, partitioning water and solute flow, filtering and buffering, nutrient cycling, and providing support for plants and other structures. Soil management has a major impact on soil quality. Soil quality relates to soil functions. Unlike water ...
Soil structure affects aeration, water movement, conduction of heat, plant root growth and resistance to erosion. [26] Water, in turn, has a strong effect on soil structure, directly via the dissolution and precipitation of minerals, the mechanical destruction of aggregates [27] and indirectly by promoting plant, animal and microbial growth.
The Atterberg limits are a basic measure of the critical water contents of a fine-grained soil: its shrinkage limit, plastic limit, and liquid limit. Depending on its water content, soil may appear in one of four states: solid, semi-solid, plastic and liquid. In each state, the consistency and behavior of soil are different, and consequently so ...