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A person with an acute febrile respiratory illness with clinical, radiological, or histopathological evidence of pulmonary parenchymal disease (e.g., pneumonia or acute respiratory distress Syndrome), an inconclusive MERS-CoV laboratory test (that is, a positive screening test without confirmation), and a resident of or traveler to Middle ...
The virus, which causes Middle East respiratory syndrome (MERS), is a novel coronavirus that was first identified in a patient from Jeddah, Saudi Arabia on 6 June 2012. Sporadic cases, small clusters, and large outbreaks have been reported in 24 countries, with over 2,600 cases of the virus and over 900 deaths, as of 2021.
3D model of a MERS-CoV spike protein. The virus appears to have originated in bats. [32] The virus itself has been isolated from a bat. [33] This virus is closely related to the Tylonycteris bat coronavirus HKU4 and Pipistrellus bat coronavirus HKU5. [34] Serological evidence shows that these viruses have infected camels for at least 20 years.
The virus was independently described in 2005 as HCoV-NH following a discovery among a group of children having respiratory infection in New Haven, Connecticut, US. [79] The origin of the virus remains a mystery, but it is closely related to tricolored bat ( Perimyotis subflavus ) coronavirus and can survive in bat cell lines, suggesting that ...
The virus can spread to different organs throughout the chicken. [131] The virus is transmitted by aerosol and food contaminated by feces. Different vaccines against IBV exist and have helped to limit the spread of the virus and its variants. [127] Infectious bronchitis virus is one of a number of strains of the species Avian coronavirus. [133]
The betacoronaviruses of the greatest clinical importance concerning humans are OC43 and HKU1 (which can cause the common cold) of lineage A, SARS-CoV-1 and SARS-CoV-2 (the causes of SARS and COVID-19 respectively) of lineage B, [2] and MERS-CoV (the cause of MERS) of lineage C. MERS-CoV is the first betacoronavirus belonging to lineage C that ...
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Human coronaviruses are capable of causing illnesses ranging from the common cold to more severe diseases such as Middle East respiratory syndrome (MERS, fatality rate ~34%). SARS-CoV-2 is the seventh known coronavirus to infect people, after 229E , NL63 , OC43 , HKU1 , MERS-CoV , and the original SARS-CoV .