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Consistency and viscosity affect the adhesion and retention property of the gel, and are important in ensuring the gel is retained at the site of application and effective delivery of the drug. [ 3 ] The ingredients in topical gel formulation can be broadly categorized into four types: gelator, solvent, drug, and excipients.
name UK Trade name Concentration (%) Maximum dose (mg/kg) Articaine with adrenaline Bartinest Septanest 4 7 Bupivacaine Marcain 0.25 2.5 Lidocaine 1 3 2 Lidocaine with adrenaline Utilycaine Lignospan Special Xylocaine 1 7 2 Mepivacaine Scandonest 2 1.36 (3 mg per pound), less than 400 mg in adults 3 Prilocaine with Felypressin Citanest 0.5 7 1
Cinchocaine (INN/BAN) or dibucaine is an amide local anesthetic.Among the most potent and toxic of the long-acting local anesthetics, current use of cinchocaine is generally restricted to spinal and topical anesthesia.
Povidone-iodine (PVP-I), also known as iodopovidone, is an antiseptic used for skin disinfection before and after surgery. [1] [2] It may be used both to disinfect the hands of healthcare providers and the skin of the person they are caring for. [2]
Many local anesthetics fall into two general chemical classes, amino esters (top) and amino amides (bottom). A local anesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness, [1] providing local anesthesia, as opposed to a general anesthetic, which eliminates all sensation in the entire body and causes ...
Bupivacaine, marketed under the brand name Marcaine among others, is a medication used to decrease sensation in a specific small area. [5] In nerve blocks, it is injected around a nerve that supplies the area, or into the spinal canal's epidural space. [5] It is available mixed with a small amount of epinephrine to increase the duration of its ...
The name ropivacaine refers to both the racemate and the marketed S-enantiomer. Ropivacaine hydrochloride is commonly marketed by AstraZeneca under the brand name Naropin . History
Polyhexanide (polyhexamethylene biguanide, PHMB) is a polymer used as a disinfectant and antiseptic.In dermatological use, [4] it is spelled polihexanide and sold under various brand names. [5]
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