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Coronary ischemia, myocardial ischemia, [1] or cardiac ischemia, [2] is a medical term for abnormally reduced blood flow in the coronary circulation through the coronary arteries. [3] Coronary ischemia is linked to heart disease , and heart attacks . [ 4 ]
The artery supplies the anterior region of the left ventricle, including: the anterolateral myocardium, apex, anterior interventricular septum, and anterolateral papillary muscle. [8] The LAD typically supplies 45–55% of the left ventricle and is therefore considered the most critical vessel in terms of myocardial blood supply. [citation needed]
Ischemia or ischaemia is a restriction in blood supply to any tissue, muscle group, or organ of the body, causing a shortage of oxygen that is needed for cellular metabolism (to keep tissue alive). [ 3 ] [ 4 ] Ischemia is generally caused by problems with blood vessels , with resultant damage to or dysfunction of tissue i.e. hypoxia and ...
Myocardial infarction; Other names: Acute myocardial infarction (AMI), heart attack: A myocardial infarction occurs when an atherosclerotic plaque slowly builds up in the inner lining of a coronary artery and then suddenly ruptures, causing catastrophic thrombus formation, totally occluding the artery and preventing blood flow downstream to the heart muscle.
The circumflex artery supplies the posterolateral left ventricle and the anterolateral papillary muscle. It also supplies the sinoatrial nodal artery in 38% of people. It supplies 15–25% of the left ventricle in right-dominant systems. If the coronary anatomy is left-dominant, the circumflex artery supplies 40–50% of the left ventricle.
It is often a sign of myocardial ischemia, of which coronary insufficiency is a major cause. Other ischemic heart diseases causing ST depression include: Subendocardial ischemia [3] or even infarction. [4] Subendocardial means non full thickness ischemia. In contrast, ST elevation is transmural (or full thickness) ischemia; Non Q-wave ...
The anterolateral papillary muscle more frequently receives two blood supplies: left anterior descending (LAD) artery and the left circumflex artery (LCX). [5] It is therefore more frequently resistant to coronary ischemia (insufficiency of oxygen-rich blood).
Papillary muscle rupture can be caused by a myocardial infarction, and dysfunction can be caused by ischemia. Rarely, blunt chest trauma can be the cause of papillary muscle rupture, resulting from the sudden deceleration or compression of the heart. [4] Complications may lead to worsening of mitral regurgitation. [5]