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Recurrent scratching, especially over the same area can lead to skin thickening which may prevent some medications from effectively working to treat the chronic itch. Senile pruritus can have a significant impact on the quality of life.
The efficacy of rupatadine as treatment for allergic rhinitis (AR) and chronic idiopathic urticaria (CIU) has been investigated in adults and adolescents (aged over 12 years) in several controlled studies, showing a rapid onset of action and a good safety profile even in prolonged treatment periods of a year. [5] [6] [7]
Fexofenadine is used for relief from physical symptoms associated with seasonal allergic rhinitis and for treatment of hives, including chronic urticaria. [12] It does not cure, but rather prevents the aggravation of allergic rhinitis and chronic idiopathic urticaria, and reduces the severity of the symptoms associated with those conditions, providing relief from repeated sneezing, runny nose ...
One of the most prevalent forms of adverse drug reactions is cutaneous reactions, [1] with drug-induced urticaria ranking as the second most common type, preceded by drug-induced exanthems. [2] Urticaria, commonly known as hives , manifests as weals, itching, burning, redness, swelling, and angioedema —a rapid swelling of lower skin layers ...
However, the understanding of urticaria as an autoimmune condition is a relatively recent development in medical history. [14] The term autoimmune urticaria refers to a subset of chronic spontaneous urticaria (CSU) cases where the immune system appears to play a significant role. This understanding began to evolve in the mid to late 20th ...
Omalizumab, sold under the brand name Xolair among others, is an injectable medication to treat severe persistent allergic forms of asthma, nasal polyps, urticaria (hives), [10] [11] and immunoglobulin E-mediated food allergy.
Ketotifen is an antihistamine medication and a mast cell stabilizer used to treat allergic conditions such as conjunctivitis, asthma, and urticaria (hives).Ketotifen is available in ophthalmic (eye drops or drug-eluting contact lenses) and oral (tablets or syrup) forms: the ophthalmic form relieves eye itchiness and irritation associated with seasonal allergies, while the oral form helps ...
Chronic spontaneous urticaria, despite its cause being unknown, is linked to a higher prevalence of autoimmune diseases, and is often worsened by triggers like stress, infections, certain foods, or nonsteroidal anti-inflammatory drugs. The hives and angioedema seen in CSU is thought to be linked to the degranulation of skin mast cells.