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Cholera is caused by a number of types of Vibrio cholerae, with some types producing more severe disease than others. [2] It is spread mostly by unsafe water and unsafe food that has been contaminated with human feces containing the bacteria. [2] Undercooked shellfish is a common source. [9] Humans are the only known host for the bacteria. [2]
Some strains of V. cholerae are pathogenic to humans and cause a deadly disease called cholera, which can be derived from the consumption of undercooked or raw marine life species or drinking contaminated water. [2] V. cholerae was first described by Félix-Archimède Pouchet in 1849 as some kind of protozoa.
A cholera outbreak in Syria has already killed at least 33 people, posing a danger across the frontlines of the country's 11-year-long war and stirring fears in crowded camps for the displaced.
Cholera toxin (also known as choleragen and sometimes abbreviated to CTX, Ctx or CT) is an AB5 multimeric protein complex secreted by the bacterium Vibrio cholerae. [ 1 ] [ 2 ] CTX is responsible for the massive, watery diarrhea characteristic of cholera infection. [ 3 ]
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President Hakainde Hichilema says some slums in urban areas are a breeding ground for the disease.
The 2010s Haiti cholera outbreak was the first modern large-scale outbreak of cholera—a disease once considered beaten back largely due to the invention of modern sanitation. The disease was reintroduced to Haiti in October 2010, not long after the disastrous earthquake earlier that year, and since then cholera has spread across the country ...
Human volunteers took part in an NIH-sponsored series of tests to develop an effective cholera vaccine. At this time, new outbreaks of cholera were occurring in Egypt, South Korea, and the Soviet Union. [16] The 1964 invention of use of oral rehydration salts (ORS) to treat cholera was endorsed by WHO in the 1980s. This practice of replacing ...