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DOTA-TATE can be reacted with the radionuclides gallium-68 (T 1/2 = 68 min), lutetium-177 (T 1/2 = 6.65 d) and copper-64 (T 1/2 = 12.7 h) to form radiopharmaceuticals for positron emission tomography (PET) imaging or radionuclide therapy. 177 Lu DOTA-TATE therapy is a form of peptide receptor radionuclide therapy (PRRT) which targets ...
The parent isotope 68 Ge has a half-life of 271 days and can be easily utilized for in-hospital production of generator produced 68 Ga. Its decay product gallium-68 (with a half-life of only 68 minutes, inconvenient for transport) is extracted and used for certain positron emission tomography nuclear medicine diagnostic procedures, where the ...
Gallium-67 (67 Ga) has a half-life of 3.26 days and decays by electron capture and gamma emission (in de-excitation) to stable zinc-67. It is a radiopharmaceutical used in gallium scans (alternatively, the shorter-lived gallium-68 may be used). This gamma-emitting isotope is imaged by gamma camera.
Gallium-67 citrate is produced by a cyclotron. Charged particle bombardment of enriched Zn-68 is used to produce gallium-67. The gallium-67 is then complexed with citric acid to form gallium citrate. The half-life of gallium-67 is 78 hours. [45] It decays by electron capture, then emits de-excitation gamma rays that are detected by a gamma camera.
This is a list of radioactive nuclides (sometimes also called isotopes), ordered by half-life from shortest to longest, in seconds, minutes, hours, days and years. Current methods make it difficult to measure half-lives between approximately 10 −19 and 10 −10 seconds. [1]
The radioactive atom, gallium-68 (68 Ga), decays with a half-life of approximately 68 min to the stable isotope zinc-68 (68 Zn), to 89% by β + decay whereby a positron with a maximum kinetic energy of 1.9 MeV is emitted (the remaining 11% are EC decays).
Gallium-70 can decay through both beta minus decay and electron capture. Gallium-67 is unique among the light isotopes in having only electron capture as a decay mode, as its decay energy is not sufficient to allow positron emission. [31] Gallium-67 and gallium-68 (half-life 67.7 min) are both used in nuclear medicine.
68 Ga is a positron emitter, with a 68-minute half-life, produced by elution from germanium-68 in a gallium-68 generator or by proton irradiation of zinc-68. Name Investigation