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Methylprednisolone acetate, sold under the brand names Depo-Medrol among others, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester—specifically the C21 acetate ester of methylprednisolone—which is used in clinical and veterinary medicine.
Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol) is a synthetic glucocorticoid, primarily prescribed for its anti-inflammatory and immunosuppressive effects. [4] [5] [6] It is either used at low doses for chronic illnesses or used concomitantly at high doses during acute flares.
Methylprednisolone succinate, sold under the brand name Solu-Medrol among others, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester—specifically the C21 succinate ester of methylprednisolone—which is used by intravenous administration.
There is a lack of evidence that FIP as such is transmissible from cat to cat, although it may explain rare mini-outbreaks of FIP. [8] However, the virus, FCov, is transmissible from cat to cat. A study on 59 FIP infected cats found that, unlike FCoV, feces from FIP infected cats were not infectious to laboratory cats via oronasal route. [9]
Lysine is commonly used as a treatment; however, in a 2015 systematic review, the authors investigated all clinical trials with cats as well as in vitro studies and concluded that lysine supplementation is likely not effective for the treatment or prevention of feline herpesvirus 1 infection. [15]
Feline idiopathic cystitis begins as an acute non-obstructive episode and is self-limiting in about 85% of cases, resolving itself in a week. In approximately 15% of cases, it can escalate into an obstructive episode ("blocked cat") which can be life-threatening for a male cat. [5]
A 2016 systematic review has found that periodontal therapy (the use of mouthwash, tooth brushing, and manual removal of dental plaques) may have a role as an added treatment for short- and long-term follow up. For these results to be confirmed with regards eradication and non-recurrence, larger studies need to be carried out. [11]
Remdesivir was never tested in cats (though some vets now offer it [1]), but GS-441524 has been found to be effective treatment for FIP. It is widely used despite no official FDA approval due to Gilead's refusal to license this drug for veterinary use.