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  2. History of United States drug prohibition - Wikipedia

    en.wikipedia.org/wiki/History_of_United_States...

    The rate of opiate addiction increased from about .72 addicts per 1,000 people to a high of 4.59 per 1,000 in the 1890s. [ 2 ] Efforts to regulate the sale of pharmaceuticals began around 1860, and laws were introduced on a state-to-state basis that created penalties for mislabeling drugs, adulterating them with undisclosed narcotics, and ...

  3. The Legislation of Morality - Wikipedia

    en.wikipedia.org/wiki/The_Legislation_of_Morality

    Addiction was managed quietly, in secret, and caused little social disturbance as long as the tonics and syrups were easily purchased from legal sources. [ 3 ] [ 4 ] Almost overnight the Harrison Narcotics Tax Act (1914) made thousands of already addicted people dependant on physicians to prescribe the drug for them.

  4. Opium - Wikipedia

    en.wikipedia.org/wiki/Opium

    Between 150,000 and 200,000 opiate addicts lived in the United States in the late 19th century and between two-thirds and three-quarters of these addicts were women. [ 38 ] Opium addiction in the later 19th century received a hereditary definition.

  5. Laudanum - Wikipedia

    en.wikipedia.org/wiki/Laudanum

    Laudanum. Laudanum is a tincture of opium containing approximately 10% powdered opium by weight (the equivalent of 1% morphine). [1] Laudanum is prepared by dissolving extracts from the opium poppy (Papaver somniferum) in alcohol (ethanol). Reddish-brown in color and extremely bitter, laudanum contains several opium alkaloids, including ...

  6. First Opium War - Wikipedia

    en.wikipedia.org/wiki/First_Opium_War

    In the early 19th century, American merchants joined the trade and began to introduce opium from Turkey into the Chinese market—this supply was of lesser quality but cheaper, and the resulting competition among British and American merchants drove down the price of opium, leading to an increase in the availability of the drug for Chinese ...

  7. Opioid epidemic in the United States - Wikipedia

    en.wikipedia.org/wiki/Opioid_epidemic_in_the...

    Total drug overdose deaths in the United States. There is an ongoing opioid epidemic (also known as the opioid crisis) in the United States, originating out of both medical prescriptions and illegal sources. It has been called "one of the most devastating public health catastrophes of our time". The opioid epidemic unfolded in three waves.

  8. Alfred R. Lindesmith - Wikipedia

    en.wikipedia.org/wiki/Alfred_R._Lindesmith

    Alfred R. Lindesmith. Advocacy of a medical approach to drug addiction. Alfred Ray Lindesmith (August 3, 1905 – February 14, 1991) was an Indiana University professor of sociology. He was among the early scholars providing a rigorous and thoughtful account of the nature of addiction. He was a critic of legal prohibitions against addictive ...

  9. Opioid use disorder - Wikipedia

    en.wikipedia.org/wiki/Opioid_use_disorder

    Opioid use disorder (OUD) is a substance use disorder characterized by cravings for opioids, continued use despite physical and/or psychological deterioration, increased tolerance with use, and withdrawal symptoms after discontinuing opioids. [12] Opioid withdrawal symptoms include nausea, muscle aches, diarrhea, trouble sleeping, agitation ...