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The two primary methods are testing for the female pregnancy hormone (human chorionic gonadotropin (hCG)) in blood or urine using a pregnancy test kit, and scanning with ultrasonography. [1] Testing blood for hCG results in the earliest detection of pregnancy. [ 2 ]
The term "rabbit test" was first recorded in 1949, and was the origin of a common euphemism, "the rabbit died", for a positive pregnancy test. [4] The phrase was, in fact, based on a common misconception about the test. While many people assumed that the injected rabbit would die only if the woman was pregnant, in fact all rabbits used for the ...
A wave of more effective laws requiring blood tests for both partners were passed by state legislatures between 1935 and 1950, beginning with Connecticut's "premarital examination law", which served as a model for other states. The Connecticut law required both parties undergo a blood test for syphilis and a physical examination. [7]
The indirect Coombs test is used in prenatal testing of pregnant women and in testing prior to a blood transfusion. The test detects antibodies against foreign red blood cells. In this case, serum is extracted from a blood sample taken from the patient. The serum is incubated with foreign red blood cells of known antigenicity. Finally, anti ...
The frog test had been a highly dependable pregnancy testing method since the 1930s until the immunological test was presented in the 1960s. [12] Pharmacists would inject the female's early urine sample into the frogs and confirm their pregnancy with the spawning of eggs within 18 hours. However, there was a critical prerequisite for accurately ...
Human chorionic gonadotropin is a glycoprotein composed of 237 amino acids with a molecular mass of 36.7 kDa, approximately 14.5kDa αhCG and 22.2kDa βhCG. [4]It is heterodimeric, with an α (alpha) subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and a β (beta) subunit that is unique to hCG.
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