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Red blood cell concentrates, also known as red cell concentrates or packed red blood cells, are red blood cells that have been separated for blood transfusion. [1] A red blood cell concentrate typically has a haematocrit of 0.50 – 0.70 L/L and a volume between 250 and 320 mL.
The packed cell volume (PCV) can be determined by centrifuging EDTA-treated or heparinized blood in a capillary tube (also known as a microhematocrit tube) at 10,000 RPM for five minutes. [12] This separates the blood into layers. The volume of packed red blood cells divided by the total volume of the blood sample gives the PCV.
By multiplying the mean cell volume by the red blood cell count, the hematocrit (HCT) or packed cell volume (PCV), a measurement of the percentage of blood that is made up of red blood cells, can be derived; [66] and when the hematocrit is performed directly, the mean cell volume may be calculated from the hematocrit and red blood cell count.
Packed red blood cells, fresh frozen plasma, and platelets are generally administered. [131] Typical ratios of fresh frozen plasma, platelets and packed red blood cells are between 1:1:1 and 1:1:2. [132] In some locations, blood has begun to be administered pre-hospital in an effort to reduce preventable deaths from significant blood loss.
After this process, the blood is stored, and within a short duration is used. Blood can be given as a whole product or the red blood cells separated as packed red blood cells. Blood is often transfused when there is known anaemia, active bleeding, or when there is an expectation of serious blood loss, such as prior to an operation.
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Packed cell volume, a clinical test; Palm Creek virus, a virus; Polycythemia vera, a disease; Polypoidal choroidal vasculopathy, an eye disease;
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