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Dapagliflozin, sold under the brand names Farxiga (US) and Forxiga (EU) among others, is a medication used to treat type 2 diabetes. [6] [7] [9] It is also used to treat adults with heart failure and chronic kidney disease. [10] [11] [7] It reversibly inhibits sodium-glucose co-transporter 2 (SGLT-2) in the renal proximal convoluted tubule to ...
A greater number of cardiovascular events was observed during the first 30 days in study subjects who received canagliflozin (0.45%) compared those who received placebo (0.07%), suggesting an early period of increased cardiovascular risk. In addition, there was an increased risk of stroke in subjects who received canagliflozin.
SGLT2 inhibitor. SGLT2 inhibitors (also called gliflozins or flozins) are a class of medications that inhibit sodium-glucose transport proteins in the nephron (the functional units of the kidney ), unlike SGLT1 inhibitors that perform a similar function in the intestinal mucosa. The foremost metabolic effect of this is to inhibit reabsorption ...
A bid by GSK and other drugmakers to stop more than 70,000 lawsuits in Delaware over discontinued heartburn drug Zantac has received the backing of leading U.S. industry groups, including the ...
June 20, 2024 at 1:25 PM. (Reuters) - The World Health Organization on Thursday issued warnings on fake drugs claiming to contain the active ingredient found in Novo Nordisk's diabetes drug ...
Another case was dismissed by a judge shortly before a trial was set to begin on May 23. Sanofi has settled about 4,000 Zantac cases, and the Financial Times reported last month that Pfizer had ...
Thiazolidinedione. The thiazolidinediones / θaɪ.əˌzoʊlɪdiːnˈdaɪ.oʊn /, abbreviated as TZD, also known as glitazones after the prototypical drug ciglitazone, [1] are a class of heterocyclic compounds consisting of a five-membered C 3 NS ring. The term usually refers to a family of drugs used in the treatment of diabetes mellitus type 2 ...
A new report by threat researchers at McAfee found 176,871 phishing emails and 449 malicious websites tied to offers of Ozempic, Wegovy and semaglutide, the generic name for these drugs, from ...